PHYTOTIDE CRF
Cellular Renewal Factor for deep skin rejuvenation.
what is phytotide crf?

Phytotide® CRF is a clinically studied, dermatologically approved skin matrix renewal complex with advanced peptides and rejuvenating factors to boost complexion and assist with post-treatment recovery for advanced aesthetic procedures.
Phytotide CRF targets the underlying causes of photodamage, offering a comprehensive approach to skin health.
Phytotide CRF ensures deep penetration of its active ingredients, maximizing their efficacy and delivering visible results. This targeted delivery system encourages a more pronounced healing response, effectively diminishing signs of aging and photodamage, including fine lines, wrinkles, and uneven skin tone.
Volume: 2ml/ampoule. 5 ampoules ber box
- Minimal to no downtime
- The procedure is done in 30-45 min
- Post-treatment recovery
- Boost combined results
MAIN INGREDIENTS
Tranexamic acid (TXA), sh-Oligopeptide-1, Copper Peptide
INGREDIENTS EXPLAINED
Tranexamic Acid (TXA)
Works to significantly reduce hyperpigmentation and sun-induced dark spots, restoring clarity and evenness to your complexion. Tranexamic Acid is a synthetic derivative of the amino acid lysine. It’s known for its powerful anti-inflammatory and depigmentation properties.
Benefits: Clinically proven to reduce hyperpigmentation, Tranexamic Acid works by inhibiting the plasminogen/plasmin pathway in the skin, which can trigger melanogenesis in response to UV exposure. It’s effective in treating melasma, sunspots, and post-inflammatory hyperpigmentation, offering a more even skin tone. Additionally, its anti-inflammatory capabilities help soothe the skin and reduce redness, making it ideal for post-procedure care.
Oligopeptide-1 (Epidermal Growth Factor or EGF)
Known for its potent regenerative properties, accelerates the healing process, smoothing wrinkles and enhancing skin texture.Oligopeptide-1, also known as EGF, is a peptide consisting of 53 amino acids. It plays a crucial role in cell growth, proliferation, and wound-healing processes.
Benefits: By mimicking the natural growth factors in the skin, Oligopeptide-1 promotes the repair and regeneration of damaged skin tissues. It accelerates healing, reduces the appearance of wrinkles, and enhances skin texture and elasticity. Its regenerative properties are particularly beneficial in rejuvenating photo-damaged skin and improving the outcome of clinical skin treatments.
Copper Peptides (GHK-Cu)
Celebrated for their anti-aging benefits, support collagen production, firming and revitalizing the skin for a youthful, resilient appearance. Copper Peptides, specifically GHK-Cu, are small, naturally occurring protein fragments that have a high affinity for copper ions. They are known for their role in the body’s natural healing processes.
Benefits: Copper Peptides offer a multitude of skin benefits, including stimulating collagen and elastin production, enhancing antioxidant activity, and promoting the removal of damaged collagen and elastin from the skin. This results in firmer, smoother skin with reduced fine lines and wrinkles. They also possess anti-inflammatory properties, further supporting skin recovery and reducing the likelihood of scarring post-treatment.
The combination of these ingredients in Phytotide CRF creates a powerful synergy that addresses the multifaceted nature of photodamage and ageing. Tranexamic Acid targets and reduces pigmentation issues, Oligopeptide-1 accelerates cellular repair and renewal, and Copper Peptides reinforce skin structure and resilience. Together, they work to rejuvenate the skin, enhance its texture and tone, and provide robust protection against future damage.
efficacy


Advanced Active Complex
Phytotide® CRF is a clinically researched combination of advanced micro-encapsulated hyaluronic acid, tranexamic acid, copper peptide (GHK-CU) and Sh-Oligopeptide-1 to address dermatological concerns in UV damage.
Skin Tone
Throughout the treatments, hyperpigmentation is observed to be visibly reduced, and the overall skin tone becomes brighter, and more even. Developed for all Fitzpatrick skin types.
Skin Texture
The deep rejuvenation of the skin matrix means that the depths of wrinkles and fine lines are visibly reduced. The skin is observed to be firmer, and smoother as the pores become more refined. The skin becomes more youthful.
Combined Treatment
Suitable for post-injectable recovery. Integrated with laser and other energy-based aesthetic treatment protocols.
Before and After


Skin Concerns
Post-Treatment Recovery
Erythema (Redness) and Inflammation
Hyperpigmentation
Skin Texture Improvements
Skin Tightening and Elasticity
Overall Skin Rejuvenation
How It Works
The combination of Tranexamic Acid, Oligopeptide-1, and Copper Peptides in the Phytotide CRF formula targets photo-damaged skin with a multifaceted approach, addressing the root causes of photodamage at a cellular level.
Combined Effects on Photo-Damaged Skin
Enhanced Skin Barrier: Together, these ingredients strengthen the skin’s barrier function, making it more resilient against environmental stressors and preventing moisture loss. A healthy barrier is essential for maintaining skin hydration and elasticity, which are often compromised in photo-damaged skin.
Cellular Turnover and Repair: The formula encourages the removal of damaged skin cells and their replacement with healthy ones. This turnover diminishes the appearance of photo-damage markers, such as fine lines, wrinkles, and uneven skin texture.
Inflammation Reduction: The anti-inflammatory actions of these ingredients help soothe the skin, reducing redness and calming irritation that can exacerbate the appearance of photodamage.
Melanin Regulation: By targeting melanin production pathways, the formula addresses the root cause of hyperpigmentation, leading to a significant improvement in the appearance of sunspots and age spots.
delivery method
SKIN NEEDLING
Therapists combine Phytotide CRF with skin needling, following standard protocols for both treatments. The same contraindications apply. After the needling session, therapists apply Phytotide CRF to the treated area, using the entire ampoule per treatment. Maintaining a needle depth of 1.5mm or less is advised for safety. A series of 4-6 treatments, spaced 4 weeks apart, is recommended for optimal results. This integrated approach offers clients effective and safe skincare treatments.

TOPICAL APPLICATION
Procedure: Phytotide CRF can also be applied directly to the skin as part of a daily skincare routine or immediately following clinical treatments that do not breach the skin barrier significantly.
Mechanism of Action: When applied directly, the active ingredients interact with the skin’s surface to reduce inflammation, protect against oxidative damage, and support the skin barrier. This method is suitable for more superficial skin concerns, including minor discolourations, surface-level texture irregularities, and maintenance of skin health.
Benefits: Direct application ensures that the skin is continuously exposed to Tranexamic Acid, Oligopeptide-1, and Copper Peptides, promoting gradual improvement in skin tone, texture, and hydration. It’s an accessible option that complements professional treatments or serves as a standalone regimen for daily skin rejuvenation.